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Inform clients that: Tramadol Hydrochloride Extended-Release is for oral use only and may be swallowed whole. The capsule should not be chewed, dissolved, crushed or break up. Tramadol Hydrochloride Prolonged-Launch may possibly lead to seizures and/or serotonin syndrome with concomitant utilization of serotonergic agents (such as SRIs, NRIs, and t